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Original Article

Prevalence of Vitamin D Deficiency and Hypervitaminosis D Among Adult Patients Admitted to the Tertiary Care Hospitals in Turkey

Dilek Gogas Yavuz 1 , Reyhan Ersoy 2 , Yüksel Altuntaş 3 , Habip Bilen 4 , Barış Pamuk 5 , Tuğçe Apaydın 1 , Şule Temizkan 6 , Hasan Altuntaş 7 , Meral Mert 8 , Ayşen Akalın 9 , Murat Sert 10 , Ilgın Yıldırım Şimşir 11 , Zeliha Hekimsoy 12 , Zeynep Cantürk 13 , Ziynet Alphan Üç 14 , Süleyman İplikçi 15 , Mehmet Yaşar 16 , Mustafa Unubol 17 , Kerem Sezer 18 , Ömercan Toplaoğlu 19 , Özlem Turhan İyidir 20 , Zafer Pekkolay 21 , Ayşegül Atmaca 22 , Oğuz Dikbaş 23 , Nilüfer Özdemir 24 , Kamile Gül 25 , Ferhat Deniz 26 , Eda Ertörer 27 , Züleyha Karaca 28 , Gülşah Elbüken 29 , Dilek Arpacı 30 , Kemal Ağbaht 31 , Elif Turan 32 , İnan Anaforoğlu 33 , Taner Bayraktaroğlu 30 , Goncagül Haklar 34 , Gülçin Dağlıoğlu 10 , Alparaslan Tuzcu 21 , İbrahim Şahin 19 , Şevki Çetinkalp 11
1.

Department of Endocrinology and Metabolism, Marmara University Faculty of Medicine, İstanbul, Turkey

2.

Department of Endocrinology and Metabolism, Ankara City Hospital, Ankara Yıldırım Beyazıt University Faculty of Medicine, Ankara, Turkey

3.

Department of Endocrinology and Metabolism, University of Health Sciences İstanbul Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, Turkey

4.

Department of Endocrinology and Metabolism, Atatürk University Faculty of Medicine, Erzurum, Turkey

5.

Department of Endocrinology and Metabolism, İzmir Katip Çelebi University Atatürk Training and Research Hospital, İzmir, Turkey

6.

Department of Endocrinology and Metabolism, Kartal Lütfi Kırdar Research and Training Hospital, İstanbul, Turkey

7.

Department of Endocrinology and Metabolism, Akdeniz University Faculty of Medicine, Antalya, Turkey

8.

Department of Endocrinology and Metabolism, Health Sciences University Faculty of Medicine Sadi Konuk Training and Research Hospital, İstanbul, Turkey

9.

Department of Endocrinology and Metabolism, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Turkey

10.

Department of Endocrinology and Metabolism, Çukurova University Faculty of Medicine Balçalı Hospital, Adana, Turkey

11.

Department of Endocrinology and Metabolism, Ege University Faculty of Medicine, İzmir, Turkey

12.

Department of Endocrinology and Metabolism, Celal Bayar University Faculty of Medicine, Manisa, Turkey

13.

Kocaeli University, Medical Faculty, Endocrinology and Metabolism, Kocaeli, Turkey

14.

Department of Endocrinology and Metabolism, Uşak University Faculty of Medicine, Uşak, Turkey

15.

Department of Endocrinology and Metabolism, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey

16.

Department of Endocrinology and Metabolism, İstanbul Taksim Research and Training Hospital, İstanbul, Turkey

17.

Department of Endocrinology and Metabolism, Aydın Adnan Menderes University Faculty of Medicine, Aydın, Turkey

18.

Department of Endocrinology and Metabolism, Mersin University Faculty of Medicine, Mersin, Turkey

19.

Department of Endocrinology and Metabolism, İnönü University Turgut Özal Medical Center, Malatya, Turkey

20.

Department of Endocrinology and Metabolism, Başkent University Faculty of Medicine, Ankara, Turkey

21.

Department of Endocrinology and Metabolism, Dicle University Faculty of Medicine, Diyarbakır, Turkey

22.

Department of Endocrinology and Metabolism, Ondokuz Mayis University Faculty of Medicine, Samsun, Turkey

23.

Department of Endocrinology and Metabolism, Giresun University Prof. Dr. A. İlhan Özdemir Training and Research Hospital, Giresun, Turkey

24.

Department of Endocrinology and Metabolism, Diyarbakır Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey

25.

Department of Endocrinology and Metabolism, Kahramanmaraş Sütçü İmam University Faculty of Medicine, Kahramanmaraş, Turkey

26.

Department of Endocrinology and Metabolism, University of Health Sciences İstanbul Sultan 2, Abdulhamid Han Training and Research Hospital, İstanbul, Turkey

27.

Department of Endocrinology and Metabolism, Başkent University Adana Dr. Turgut Noyan Training and Research Hospital, Adana, Turkey

28.

Department of Endocrinology and Metabolism, Erciyes University Faculty of Medicine, Kayseri, Turkey

29.

Department of Endocrinology and Metabolism, Tekirdağ Namık Kemal University Faculty of Medicine, Tekirdağ, Turkey

30.

Department of Endocrinology and Metabolism, Zonguldak Bülent Ecevit University Faculty of Medicine, Zonguldak, Turkey

31.

Department of Endocrinology and Metabolism, Defne Private Hospital, Hatay, Turkey

32.

Department of Endocrinology and Metabolism, Yozgat Bozok University Faculty of Medicine, Yozgat, Turkey

33.

Department of Endocrinology and Metabolism, Medical Park Trabzon Hospital, Trabzon, Turkey

34.

Department of Biochemistry, Marmara University Faculty of Medicine, İstanbul, Turkey

Endocrinol Res Pract 2022; 26: 79-84
DOI: 10.5152/tjem.2022.22031
Keywords : 25-Hydroxyvitamin D, vitamin D, vitamin D deficiency
Read: 2582 Downloads: 691 Published: 01 June 2022
Volume 26, Issue 2, June 2022
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Objective: Vitamin D deficiency is a common health problem around the world. This study aimed to evaluate the nationwide prevalence of vitamin D status in tertiary care hospitals in Turkey.

Methods: Retrospectively, the data on vitamin D levels from 33 tertiary care hospitals’ clinical bio- chemistry laboratories around Turkey between January and December were collected.

Results: In total, 706 434 serum samples from adult subjects (female/male: 469 028/237 406; 66.4%/33.6%) were included. While vitamin D levels were sufficient in 20.3% (n = 14 222), they were insufficient in 21.9% (n = 154 360) and deficient in 57.8% (n = 408 882).

We observed the highest rates of deficiency in those aged between 18 and 29 years (62.9%, n=70 235) and lowest rates between 60 and 69 years (52.3%, n=61 121) and between 70 and 79 years (52.3%, n=32 397). Hypervitaminosis D was detected in 5.5% of adult subjects; highest rates of hypervitaminosis D were observed in those who were over 80 years (6.6%) and 70-79 years (6.5%) and the lowest in 18-29 years (2.8%).

Discussion: In this cohort, over half of the subjects admitted to the tertiary care hospitals in Turkey had vitamin D deficiency and required vitamin D supplementation. The elderly population had the lowest prevalence of vitamin D insufficiency and the highest prevalence of hypervitaminosis D.

Cite this article as: Gogas Yavuz D, Ersoy R, Altuntaş Y, et al. Prevalence of vitamin D deficiency and hypervitaminosis D among adult patients admitted to the tertiary care hospitals in Turkey. Turk J Endocrinol Metab 2022;26(2):79-84.

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