ISSN: 1301-2193 E-ISSN: 1308-9846
  • Turkish Journal of
    Endocrinology and Metabolism

In this study, the etiopathogenesis of metabolic syndrome parameters was discussed and it was pointed out that malonyl-CoA, a lipogenic glucose metabolite, might be responsible for a common mechanism in hyperinsulinemia and insulin resistance , triglyceride synthesis and storage, cholesterol synthesis and the developmen t of ischemic heart disease.
Keywords: Malonyl-CoA, metabolic syndrome, apoptosis