In this issue of our Journal, original articles, case reports and a review take place, which I hope will arouse your interest.
In the study Resistance to thyroid hormone: Probable de novo mutation (P453S) in the receptor beta gene presented by Köroğlu et al from Isparta and evaluated together with Samuel Refetoff, it was suggested that a mutation may have occurred de novo in the father of the proband, a young male of a Turkish family. Resistance to thyroid hormone, a rarely observed syndrome, was discussed.
In an article by Gul et al from Ankara and Konya, pre- and postoperative clinical and histopathological characteristics of 224 patients with papillary thyroid microcarsinoma, accounting for 85% of thyroid carcinomas, were evaluated. Due to the high rate of multifocality and capsular invasion in their series, the authors suggested total/near total thyroidectomy followed by radioiodine therapy and suppressive therapy with L-thyroxine in papillary carcinomas independent of their size.
Yegin et al from Ankara investigated the short-term effects of melatonin on glucose homeostasis in 60 patients with type 2 diabetes mellitus and they did not detect any effect on humans in contrast to animal series.
Gul et al from Bursa draw attention to rarely observed Flatbush diabetes by presenting two cases with ketosis-prone type 2 diabetes mellitus.
Gokalp et al discussed the possible mechanisms of rarely observed Lipoid proteinosis accompanied by diabetes in a 16-year-old patient and attracted attention to mutation at lq21 locus in patients with insulin resistance.
Cakir et al from Kayseri suggested considering pituitary abscess in meningitis patients with deterioration in general health status by presenting a case with pituitary abscess in a 43-year-old patient with acute purulent meningitis.
My Dear Colleagues,
This issue appears as an enjoyable edition, that gives us opportunity to review the literature and update our knowledge, on different aspects of endocrinology, through case reports, a review and discussions, submitted from different regions of our country and some of which are evaluated together with foreign scientists.
It is supposed that the manuscripts of our young colleagues who are at the beginning of their education in endocrinology will provide valuable contributions in the evaluation of their academic development. Turk JEM anticipates submission of original articles, case reports and reviews of local and foreign authors.