ISSN: 1301-2193 E-ISSN: 1308-9846
  • Turkish Journal of
    Endocrinology and Metabolism
CASE REPORT

Thrombotic Microangiopathy After Spontaneous Pheochromocytoma Rupture: A Rare MEN 2A Case
Spontan Feokromasitoma Rüptüründen Sonra Gelişen Trombotik Mikroanjiyopati: Nadir Bir MEN 2A Olgusu
Received Date : 20 Feb 2020
Accepted Date : 29 Jun 2020
Available Online : 21 Jul 2020
Doi: 10.25179/tjem.2020-74367 - Makale Dili: EN
Turk J Endocrinol Metab. 2020;24:247-252
Bu makale, CC BY-NC-SA altında lisanslanmış açık erişim bir makaledir.
ABSTRACT
Pheochromocytoma is an adrenal medulla-derived tumor originating from the chromaffin cells that produce and secrete catecholamines. These tumors usually occur sporadically, but they may also be associated with genetic diseases, such as multiple endocrine neoplasia syndrome type 2 (MEN 2). A hypertensive crisis that occurs after the spontaneous rupture of pheochromocytoma, is a rare clinical complication with a high mortality rate. In this article, we present a male case who developed hypertensive crisis and thrombotic microangiopathy (TMA) after a spontaneous pheochromocytoma rupture due to MEN 2A.
ÖZET
Feokromasitoma, katekolamin üreten ve salgılayan kromaffin hücrelerden kaynaklanan adrenal medulla kaynaklı bir tümördür. Bu tümörler genellikle sporadik olarak ortaya çıkar, ancak multipl endokrin neoplazi sendromu tip 2 (MEN2) gibi genetik hastalıklarla da ilişkili olabilir. Spontan feokromasitoma rüptüründen sonra gelişen hipertansif kriz, nadir görülen ve mortalitesi yüksek olan klinik bir durumdur. Bu yazıda, MEN 2A'ya bağlı spontan feokromasitoma rüptürü sonrası hipertansif kriz ve trombotik mikroanjiyopati (TMA) gelişen erkek bir olgu sunmayı amaçladık.
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