ISSN: 1301-2193 E-ISSN: 1308-9846
  • Turkish Journal of
    Endocrinology and Metabolism
ORIGINAL ARTICLE

The Effect of Falsely Highlighted Intestinal Intraluminal Areas and the Fat in Paraspinal Muscles on Abdominal Adipose Tissue Measurements Using Computed Tomography
İntestinal Lümen İçerisinde Hatalı Olarak Boyanan Alanların ve Paraspinal Kaslar İçerisindeki Yağ Alanlarının Bilgisayarlı Tomografi ile Abdominal Yağ Ölçümü Üzerindeki Etkisi
Received Date : 28 Feb 2020
Accepted Date : 22 Jun 2020
Available Online : 07 Jul 2020
Doi: 10.25179/tjem.2020-74562 - Makale Dili: EN
Turk J Endocrinol Metab. 2020;24:214-220
Bu makale, CC BY-NC-SA altında lisanslanmış açık erişim bir makaledir.
ABSTRACT
Objective: The measurement of abdominal fat using computed tomography (CT) is a reliable method for evaluating metabolic disorders. However, some limitations exist with the current CT measurement methods. One of them is falsely highlighted intestinal intraluminal areas and the other one is fat in paraspinal muscles. We aimed to investigate the effects of highlighted intestinal intraluminal areas and fat in paraspinal muscles on the measured values of abdominal fat. Material and Methods: Measurements were performed on 246 abdominal CT scans of 129 patients using dedicated quantitative CT software. Visceral and subcutaneous fats were measured at the level of L1-L2 disc space using two different methods. Method 1 included the highlighted intestinal intraluminal areas and fat in paraspinal muscles for measurements, whereas method 2 excluded them. The values measured using two methods were compared for a statistically significant difference. In addition, the correlation between anthropometric data and subcutaneous adipose tissue measurement methods was analyzed. Results: The mean age of patients was 53 years, and the mean body mass index was 29.73 kg/m2. The waist circumference data were available of 91 patients, and the mean waist circumference was 94 cm. The Wilcoxon signed-rank sum test showed a statistically significant difference between methods 1 and 2 (p<0.0001). Although the measurements performed using methods 1 and 2 were strongly correlated (r>0.9), the Passing-Bablok regression analysis indicated a systematic and proportional error between measurements. Conclusion: Falsely highlighted intestinal intraluminal areas should be excluded for accurate visceral adipose tissue measurements, and the fat in paraspinal muscles affects subcutaneous fat measurement results.
ÖZET
Amaç: Bilgisayarlı tomografi (BT) ile abdominal yağ ölçümü, metabolik hastalık değerlendirmesi açısından oldukça güvenilir bir metottur. Mevcut BT ölçüm metotlarının bazı kısıtlılıkları vardır. Bu kısıtlılıklardan biri, intestinal lümen içerisinde yanıltıcı olarak boyanan alanlardır. Bir diğeri ise paraspinal kaslar içerisindeki yağ doku alanlarıdır. Çalışmamızın amacı, intestinal lümen içerisinde yanıltıcı olarak boyanan alanların ve paraspinal kaslar arasındaki yağ alanlarının abdominal yağ ölçümleri üzerindeki etkisinin araştırılmasıdır. Gereç ve Yöntemler: Yağ ölçümüne yönelik geliştirilmiş kantitatif BT yazılımı kullanılarak 129 hastanın 246 abdomen BT tetkikinde yağ ölçümleri gerçekleştirilmiştir. Viseral ve subkütan yağ ölçümleri, L1- L2 disk düzeyinden iki farklı yöntem kullanılarak gerçekleştirilmiştir. Metot 1’de, intestinal lümen içerisinde yanıltıcı olarak boyanan alanlar ve paraspinal kaslar arasındaki yağ alanları, abdominal yağ ölçümüne dâhil edilmiş, Metot 2’de ise edilmemiştir. İki metot ile ölçülen değerler istatistiksel anlamlı fark açısından karşılaştırılmıştır. Ayrıca antropometrik ölçümler ile subkütanöz yağ dokusu ölçüm metodu arasındaki korelasyon da değerlendirilmiştir. Bulgular: Ortalama hasta yaşı 53 yıl ve ortalama beden kitle indeksi 29,73 kg/m2 olarak bulunmuştur. Bel çevresi ölçümleri 91 hastada mevcut olup, ortalama bel çevresi 94 cm’dir. Wilcoxon işaretli sıralar testi uygulandığında, Metot 1 ve Metot 2 arasında istatistiksel olarak anlamlı fark saptanmıştır (p<0,0001). İki metot ölçümleri arasında güçlü bir korelasyon bulunmakla birlikte (r>0,9), Passing-Bablok analizi ile iki metot arasında sistematik ve orantılı hata saptanmıştır. Sonuç: İntestinal lümen içerisinde yanıltıcı olarak boyanan alanlar viseral yağ ölçümü uygulanırken çıkartılmalıdır. Paraspinal kaslar içerisindeki yağ ise subkütan yağ ölçüm sonuçlarını etkileyecek düzeydedir.
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