ISSN: 1301-2193 E-ISSN: 1308-9846
  • Turkish Journal of
    Endocrinology and Metabolism
CASE REPORT

Macroprolactinemia Associated with Anti-Prolactin Antibodies: A Case Report - Case Report
Macroprolactinemia Associated with Anti-Prolactin Antibodies: A Case Report - Case Report
Makale Dili: EN
ABSTRACT

Summary

Macromolecular form of prolactin is generally associated with asymptomatic hyperprolactinemia. Increases in molecular size may result from self-aggregation or binding with antiprolactin antibodies. Such a benign clinically insignificant laboratory abnormality could be documented by gel filtration chromatography, polyethylene glycol precipitation methods or directly detecting antiprolactin autoantibody itself.
Here we report a case of asymptomatic hyperprolactinemia due to macroprolactinemia associated with prolactin autoantibodies to notice the importance of clinically insignificant isolated laboratory abnormalities.
Keywords: Macroprolactinemia, antiprolactin autoantibody, hyperprolactinemia

ÖZET

Summary

Macromolecular form of prolactin is generally associated with asymptomatic hyperprolactinemia. Increases in molecular size may result from self-aggregation or binding with antiprolactin antibodies. Such a benign clinically insignificant laboratory abnormality could be documented by gel filtration chromatography, polyethylene glycol precipitation methods or directly detecting antiprolactin autoantibody itself.
Here we report a case of asymptomatic hyperprolactinemia due to macroprolactinemia associated with prolactin autoantibodies to notice the importance of clinically insignificant isolated laboratory abnormalities.
Keywords: Macroprolactinemia, antiprolactin autoantibody, hyperprolactinemia