REVIEW
Dealing with COVID-19: Through Endocrinologist’s Eyes
Endokrinologların Gözüyle COVID-19 ile Mücadele
Received Date : 27 Jul 2020
Accepted Date : 10 Nov 2020
Available Online : 10 Dec 2020
Cem SULU, Pınar KADIOĞLU
Department of Internal Medicine, Division of Endocrinology-Metabolism and Diabetes, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TURKEY
Doi: 10.25179/tjem.2020-78280 - Makale Dili: EN
Turk J Endocrinol Metab. 2020;24:335-42
ABSTRACT
Less than a year ago, none of us had heard of novel coronavirus
disease (COVID-19). Today, it has become the main
topic of our daily conversations. This disastrous disease has
united the medical professions belonging to various specialties
to fight against the disease in collaboration. However,
the exact role of endocrinologists still remains elusive. The
coronavirus could potentially infect organs other than the
lungs, such as the pancreas, thyroid, adrenal glands, and
pituitary, as reflected by various endocrinological manifestations.
The direct invasion of organ systems and indirect
mechanisms such as induction of autoimmunity could be
responsible for the endocrinological consequences. A large
body of literature on its pathophysiology, management, and
associated conditions is growing, and its association with
endocrinological diseases is increasingly being recognized.
However, data that would guide the proper management of
these endocrinological disorders during this novel pandemic
are still lacking. This review presented a brief overview of
the association of COVID-19 with endocrinological diseases
and methods to ease the management of some frequently
encountered endocrinological problems.
Keywords: COVID-19; diabetes mellitus; pituitary; thyroid; adrenal insufficiency
ÖZET
Bir yıldan az bir süre önce hiçbirimiz yeni koronavirüs hastalığı
(COVID-19) hakkında fikir sahibi değildik. Günümüzde
ise bu hastalık hayatımızın merkezine yerleşmiş vaziyette.
Virüsle mücadele için çeşitli uzmanlık branşlarından hekimler
bir araya geldiler. Bu topkeyün savaşta endokrinologlara
düşen spesifik görevler henüz net değildir. Koronavirüs akciğer
dışında pankreas, tiroid, hipofiz bezi ve adrenal bezler
gibi endokrin sisteme ait organlara da hasar vererek endokrinolojik
semptom ve bulgulara yol açabilir. Endokrinolojik
manifestasyonların altında yatan muhtemel mekanizma
organ sistemlerinin virüs tarafından invazyonu ve otoimmünitenin
tetiklenmesi ile açıklanabilir. COVID-19’un patofizyolojisi,
tedavisi ve eşlik eden komorbititeler hakkında
literatür günden güne zenginleşmekte, virüsün endokrinolojik
hastalıklar ile olan ilişkilerine ait farkındalık artmaktadır.
Buna karşın pandeminin seyrinde rastlanan
endokrinolojik problemlerin akılcı yönetimi aydınlatılmaya
muhtaçtır. Bu derleme COVID-19 ile endokrinolojik hastalıkların
arasındaki ilişkiye ışık tutmak ve COVID-19 seyrinde
sıkça rastlanılan endokrinolojik hastalıkların tedavisine yol
göstermek amacıyla yazıldı.
Anahtar Kelimeler: COVID-19; diabetes mellitus; hipofiz; tiroid; adrenal yetersizlik
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