ISSN: 1301-2193 E-ISSN: 1308-9846
  • Turkish Journal of
    Endocrinology and Metabolism
CASE REPORT

A Case of Thyrotropin-Secreting Pituitary Adenoma (TSH-oma) - Case Report
A Case of Thyrotropin-Secreting Pituitary Adenoma (TSH-oma) - Case Report
Makale Dili: EN
ABSTRACT

Summary

Thyrotropin-secreting pituitary adenomas are rare tumors, and prevalence is about one case per million. Normal or elevated thyrotropin levels in hyperthyroid patients are characteristic of TSH-secreting pituitary adenoma. Because TSH-secreting pituitary tumors are uncommon, subjects with TSH-omas are often misdiagnosed as having Graves’ disease, and misdiagnosis may leads to enlargement of tumor size. We present a patient with thyrotropin-secreting pituitary adenoma misdiagnosed as Graves’ disease. The patient has high T3, FT3, FT4 and TSH, and she has a pituitary microadenoma ( 9 mm). Once the inappropriate secretion of TSH is established, the differential diagnosis between TSH-secreting tumor and resistance to thyroid hormone must be made.
Keywords: TSH-oma, Thyrotropin, alpha subunit of TSH and Graves’ disease

ÖZET

Summary

Thyrotropin-secreting pituitary adenomas are rare tumors, and prevalence is about one case per million. Normal or elevated thyrotropin levels in hyperthyroid patients are characteristic of TSH-secreting pituitary adenoma. Because TSH-secreting pituitary tumors are uncommon, subjects with TSH-omas are often misdiagnosed as having Graves’ disease, and misdiagnosis may leads to enlargement of tumor size. We present a patient with thyrotropin-secreting pituitary adenoma misdiagnosed as Graves’ disease. The patient has high T3, FT3, FT4 and TSH, and she has a pituitary microadenoma ( 9 mm). Once the inappropriate secretion of TSH is established, the differential diagnosis between TSH-secreting tumor and resistance to thyroid hormone must be made.
Keywords: TSH-oma, Thyrotropin, alpha subunit of TSH and Graves’ disease